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Target Gene Complex Oestrogen Transcription Binds Method Initiating

Front Method of Oestrogen initiating transcription of target gene
Back Oestrogen steroid hormone, binds to transcription factor (Oestrogen receptor) forming oestrogen-oestrogen receptor complex
Complex moves from the cytoplasm into nucleus where it binds to specific DNA sites near target gene
Complex acts as activator of transcription, it helps RNA polymerase bind to start of target gene

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