Humoral immunity involves B cells binding to antigens, which are then presented on the cell surface. Activated by helper T cells and cytokines, B cells clone into plasma cells that secrete antibodies, while some become memory cells.
- specific B cell with complementary receptor binds to pathogen antigen - antigen enters cell by endocytosis - presented on cell membrane - specific helper T cell with complementary receptor binds to antigen - activates B cell - activated T cell releases cytokines - clonal selection - cytokines stimulate B cell to divide by mitosis, differentiating into plasma cells - cloned plasma cells secrete specific antibody complementary to pathogen - antibody attaches to antigens, destroys pathogen - some B cells differentiate into memory cells
Front | How does humoral immunity work? |
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Back | - specific B cell with complementary receptor binds to pathogen antigen - antigen enters cell by endocytosis - presented on cell membrane - specific helper T cell with complementary receptor binds to antigen - activates B cell - activated T cell releases cytokines - clonal selection - cytokines stimulate B cell to divide by mitosis, differentiating into plasma cells - cloned plasma cells secrete specific antibody complementary to pathogen - antibody attaches to antigens, destroys pathogen - some B cells differentiate into memory cells |
Tags: immunity
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