DNA methylation, the addition of methyl groups, can inhibit transcription by blocking the binding of transcriptional factors to the promoter, thus reducing RNA polymerase activity and protein production.
- methyl groups added to DNA - inhibits binding of transcriptional factors to promoter - so RNA polymerase is not stimulated to transcribe the gene - rate of transcription decreases - less protein produced
| Front | How does methylation of DNA work? |
|---|---|
| Back | - methyl groups added to DNA - inhibits binding of transcriptional factors to promoter - so RNA polymerase is not stimulated to transcribe the gene - rate of transcription decreases - less protein produced |
Tags: gene_expression
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