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Glucose Glucagon Concentration Converts Protein Kinase Blood Cells

Front How does glucagon work?
Back
- decrease in blood glucose concentration detected by α cell receptors
- α cells secrete glucagon

- attaches to glucagon receptor on surface of target cells
- receptor activates adenylate cyclase enzyme
- adenylate cyclase converts ATP into cyclic AMP
- cAMP acts as a second messenger and activates protein kinase

- protein kinase converts glycogen into glucose by glycogenolysis
- protein kinase converts amino acids and glycerol into glucose by gluconeogenesis

- maintains larger concentration gradient of glucose for
- more facilitated diffusion of glucose out of the cell
- increase in blood glucose concentration

Tags: homeostasis

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