The cross-bridge cycle involves ATP detaching myosin from actin, ATP hydrolysis energizing the myosin head, binding to actin to form a cross-bridge, releasing Pi, and then swiveling to pull actin, releasing ADP. The order PI then ADP is important.
- ATP attaches to myosin head - myosin head detaches from binding site on actin - ATP hydrolysed to ADP and Pi - provides energy for myosin head to return to cocked position - myosin head can bind to binding site further down the actin filament - myosin head binds to binding site on actin - cross bridge forms - Pi released - myosin head rotates using energy from ATP - moves actin filament towards centre of sarcomere - ADP released PI THEN ADP
| Front | Describe the cross bridge cycle. |
|---|---|
| Back | - ATP attaches to myosin head - myosin head detaches from binding site on actin - ATP hydrolysed to ADP and Pi - provides energy for myosin head to return to cocked position - myosin head can bind to binding site further down the actin filament - myosin head binds to binding site on actin - cross bridge forms - Pi released - myosin head rotates using energy from ATP - moves actin filament towards centre of sarcomere - ADP released |
Tags: muscles
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