| Front | Explain the sigmoid shape of an oxygen dissociation curve |
|---|---|
| Back | At low partial pressure of O2 : - polypeptide sub units closely united - difficult for first O2 to bind to Fe2+ - small initial gradient - first O2 causes change in tertiary structure and shape - causes second and third O2 to bind to Fe2+ more easily - positive cooperativity - larger gradient At high partial pressure of O2: - 3/4 haemoglobin binding sites occupied - difficult for 4th O2 to bind to Fe2+ - curve levels off |
Tags: blood
Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.
Next card: O affinity shifts direction dissociation curve conditions higher
Previous card: Haemoglobin sequence polypeptide structure vary species bases gene
Up to card list: AQA A Level Biology