Pressure deforms the Pacinian Corpuscle's membrane, opening stretch-mediated Na+ channels, allowing Na+ influx and depolarization to create a generator potential; greater pressure leads to a greater potential, potentially reaching the threshold for an action potential.
- pressure deforms membrane - stretch mediated Na+ channels open - Na+ diffuse in - depolarisation - generator potential <b>- greater pressure --> more Na+ channels open, greater influx of Na+, greater depolarisation/generator potential</b> - if generator potential reaches threshold, action potential forms
| Front | How is a generator potential established in the Parcinian Corpuscle? |
|---|---|
| Back | - pressure deforms membrane - stretch mediated Na+ channels open - Na+ diffuse in - depolarisation - generator potential - greater pressure --> more Na+ channels open, greater influx of Na+, greater depolarisation/generator potential - if generator potential reaches threshold, action potential forms |
Tags: nerves
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