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Irritation Feeling Being   About Repeatedly Long Time Heavy

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irritation

Back the feeling of being 
annoyed
https://www.ldoceonline.com/dictionary/annoy
 about something, especially something that happens repeatedly or for a long time
 

The heavy traffic is a constant source of irritation.

something that makes you annoyed

 
The children are just an irritation for him when he’s trying to work.

 a 
painful
https://www.ldoceonline.com/dictionary/painful
 
sore
https://www.ldoceonline.com/dictionary/sore
 feeling on a part of your body
 

The astringent can cause irritation to sensitive skin.

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