Mutant A1AT accumulates in the endoplasmic reticulum of hepatocytes, resulting in liver damage and potentially cirrhosis in patients with A1AT deficiency.
Mutantes A1AT sammelt sich im endoplasmatischen Retikulum von Hepatozyten an, was zu Leberschäden führt.
Front | Why might liver cirrhosis be present in patients with an A1AT deficiency? |
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Back | Mutant A1AT accumulates in the endoplasmic reticulum of hepatocytes, resulting in liver damage. |
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