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Clot  Clotting Factors Activate Platelets Initiate Localised Vasoconstriction

The coagulation cascade involves clotting factors activating platelets and prothrombin to thrombin, thrombin converting fibrinogen to fibrin to form a clot, and plasmin dissolving the clot upon repair.

The coagulation cascade involves steps where clotting factors activate platelets, initiate vasoconstriction, and convert prothrombin to thrombin. Thrombin then converts fibrinogen to fibrin, which forms a mesh trapping blood cells. Plasmin later dissolves the clot once the damage is repaired.

Original 1. clotting factors activate platelets, initiate localised vasoconstriction, trigger activation of prothrombin to thrombin 
2. thrombin catalyses the converison of fibrinogen to fibrin 
3. fibrin forms a mesh of fibres around platelet plug and traps blood cells to form clot 
4. when damage is repairs plasmin activated to dissolve the clot 
Title steps in the coagulation cascade 
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1. clotting factors activate platelets, initiate localised vasoconstriction, trigger activation of prothrombin to thrombin 
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Text2
1. clotting factors activate platelets, initiate localised vasoconstriction, trigger activation of prothrombin to thrombin 
2. thrombin catalyses the converison of fibrinogen to fibrin 
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Text3
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2. thrombin catalyses the converison of fibrinogen to fibrin 
3. fibrin forms a mesh of fibres around platelet plug and traps blood cells to form clot 
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Text4
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3. fibrin forms a mesh of fibres around platelet plug and traps blood cells to form clot 
4. when damage is repairs plasmin activated to dissolve the clot 
Full
1. clotting factors activate platelets, initiate localised vasoconstriction, trigger activation of prothrombin to thrombin 
2. thrombin catalyses the converison of fibrinogen to fibrin 
3. fibrin forms a mesh of fibres around platelet plug and traps blood cells to form clot 
4. when damage is repairs plasmin activated to dissolve the clot 

Tags: 6_3_disease_defenses

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