Noncompetitive inhibition occurs when a molecule binds to an allosteric site, causing a conformational change in the active site that reduces its function without direct competition with the substrate, making substrate concentration changes ineffective.
La molécule se lie à un site allostérique provoquant un changement conformationnel du site actif, n'ayant plus de spécificité partagée, n'étant pas en concurrence directe avec le substrat, donc le changement des concentrations de substrat est inefficace.
| Front | the role of the signal recognition particle in protein destination |
|---|---|
| Back | presence of signal -> recruitment of SRP, halting translation until SRP-ribosome complex docks at receptor on the ER membrane, translation re-initiated and polypeptide chain grows into lumen of ER via a transport channel, synthesized protein transported via a vesicle/embedded in ER membrane, SRP cleaved and recycled |
Tags: 7_3_translation
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