Benzodiazepines enhance GABA's inhibitory effects by binding to its receptors, increasing chloride channel opening and causing hyperpolarization, which promotes sleep and muscle relaxation.
Benzodiazepines enhance GABA's inhibitory effects by binding to its receptors, increasing chloride channel opening and causing hyperpolarization, which promotes sleep and muscle relaxation.
| Front | benzodiazepine function |
|---|---|
| Back | bind to GABA receptors on the post-synaptic neuron and increase the efficiency of GABA action; GABA triggers opening of chloride channels - hyperpolarisation; promote sleep-inducing and muscle relaxing responses by the body |
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