Original | Huntingtin (HTT) gene on chromosome 4 possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats) more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats) once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood chorea and dementia |
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Title | Huntington’s disease is an autosomal dominant disorder caused by a mutation to the ... It ... but ... and ... symptoms usually ... and include |
Settings | 1,1,0 | n,n,n,n |
Text1 | Huntingtin (HTT) gene on chromosome 4 ... ... ... ... ... |
Text2 | Huntingtin (HTT) gene on chromosome 4 possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats) ... ... ... ... |
Text3 | ... possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats) more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats) ... ... ... |
Text4 | ... ... more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats) once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration ... ... |
Text5 | ... ... ... once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood ... |
Text6 | ... ... ... ... develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood chorea and dementia |
Full | Huntingtin (HTT) gene on chromosome 4 possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats) more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats) once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood chorea and dementia |
Tags: 3_4_inheritance, huntingtons
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