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Huntingtin Sequence Repeats Htt Gene Chromosome Possesses Repeating

Original
Huntingtin (HTT) gene on chromosome 4
possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats)
more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats)
once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration
develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood 
chorea and dementia
Title Huntington’s disease is an autosomal dominant disorder caused by a mutation to the ... It ... but ... and ... symptoms usually ... and include
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Huntingtin (HTT) gene on chromosome 4
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Text2
Huntingtin (HTT) gene on chromosome 4
possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats)
...
...
...
...
Text3
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possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats)
more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats)
...
...
...
Text4
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...
more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats)
once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration
...
...
Text5
...
...
...
once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration
develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood 
...
Text6
...
...
...
...
develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood 
chorea and dementia
Full
Huntingtin (HTT) gene on chromosome 4
possesses a repeating trinucleotide sequence (CAG) that is usually present in low amounts (10 – 25 repeats)
more than 28 CAG repeats is unstable and causes the sequence to amplify (produce even more repeats)
once the number of repeats exceeds ~40, the huntingtin protein will misfold and cause neurodegeneration
develop noticeably in a person’s middle age (~40 years) as this occurs in late adulthood 
chorea and dementia

Tags: 3_4_inheritance, huntingtons

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