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IB Biology HL

Pump Sites Pump.  Phosphate Group Potassium Sodium Potassium Sodium

The sodium-potassium pump binds three sodium ions, undergoes ATP-driven conformational changes to translocate sodium out, exposes potassium binding sites, and then translocates potassium in upon phosphate release.

The sodium-potassium pump facilitates ion exchange by binding three sodium ions intracellularly, undergoing a conformational change via ATP hydrolysis to translocate sodium out. This exposes potassium binding sites, and upon phosphate release, the pump returns to its original conformation, moving potassium ions in.

Original bind to intracellular sites on the sodium-potassium pump. A phosphate group is transferred to the pump via the hydrolysis of ATP. The pump undergoes a
conformational change, translocating sodium across the membrane. This exposes 
two potassium binding sites on the extracellular surface of the pump. The phosphate group is released which causes the pump to
return to its original conformation. This translocates the 
potassium ions across the membrane, completing the ion exchange 
Title Describe the process of ion exchange at the sodium-potassium pump: Three sodium ions
Settings 1,1,0 | n,n,n,n
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bind to intracellular sites on the sodium-potassium pump. 
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Text2
bind to intracellular sites on the sodium-potassium pump. 
A phosphate group is transferred to the pump via the hydrolysis of ATP
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A phosphate group is transferred to the pump via the hydrolysis of ATP
. The pump undergoes a
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. The pump undergoes a
conformational change, translocating sodium across the membrane.
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conformational change, translocating sodium across the membrane.
 This exposes 
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 This exposes 
two potassium binding sites on the extracellular surface of the pump. 
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two potassium binding sites on the extracellular surface of the pump. 
The phosphate group is released which causes the pump to
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The phosphate group is released which causes the pump to
return to its original conformation. 
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Text9
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return to its original conformation. 
This translocates the 
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Text10
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This translocates the 
potassium ions across the membrane, completing the ion exchange 
Full
bind to intracellular sites on the sodium-potassium pump. 
A phosphate group is transferred to the pump via the hydrolysis of ATP
. The pump undergoes a
conformational change, translocating sodium across the membrane.
 This exposes 
two potassium binding sites on the extracellular surface of the pump. 
The phosphate group is released which causes the pump to
return to its original conformation. 
This translocates the 
potassium ions across the membrane, completing the ion exchange 

Tags: 1_4_membrane_transport

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