Humanization is refers to the genetic engineering of mouse hypervariable loops of desired specificity into otherwise human antibodies for use as therapeutic agents, making them less likely to cause an immune response in humans compared to wholly mouse antibodies.
Humanisatie is de technologische manipulatie van muis hypervariabele lussen met de gewenste specificiteit in anders-humaan antilichamen voor gebruik als therapeutische middelen. Deze antilichamen veroorzaken doorgaans minder een immuunreactie bij mensen dan volledig muizenantilichamen.
| Front | The genetic engineering of mouse hypervariable loops of a desired specificity into otherwise human antibodies for use as therapeutic agents. Such antibodies are less likely to cause an immune response in people treated with them than are wholly mouse antibodies |
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| Back | humanization |
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