The cyclic reentry model explains B cell behavior in lymphoid follicles, proposing that activated B cells in germinal centers lose and gain CXCR4 expression, moving between the light and dark zones under the influence of CXCL12.
El modelo de reentrada cíclica explica el comportamiento de las células B en los folículos linfoides: las células B activadas en centros germinales pierden y ganan expresión de CXCR4, moviéndose entre la zona clara y oscura bajo la influencia de CXCL12.
| Front | An explanation of the behavior of B cells in lymphoid follicles, proposing that activated B cells in germinal centers lose and gain expression of the chemokine receptor CXCR4 and thus move from the light zone to the dark zone and back again under the influence of the chemokine CXCL12 |
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| Back | cyclic reentry model |
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