Antibody-dependent cell-mediated cytotoxicity (ADCC) is the killing of antibody-coated target cells by cells with Fc receptors that recognize the constant region of the bound antibody. Most of this killing is mediated by NK cells that have the Fc receptor FcγRIII on their surface.
La citotoxicidad celular dependiente de anticuerpos (ADCC) es la muerte de células diana recubiertas de anticuerpos por células con receptores Fc que reconocen la región constante del anticuerpo unido. La mayor parte de esta muerte es mediada por células NK que tienen el receptor FcγRIII en su superficie.
| Front | The killing of antibody-coated target cells by cells with Fc receptors that recognize the constant region of the bound antibody. Most of this killing is mediated by NK cells that have the Fc receptor FcγRIII on their surface |
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| Back | antibody-dependent cell-mediated cytotoxicity ADCC |
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