The peptide-binding cleft, also known as the peptide-binding groove, is a longitudinal groove on the surface of MHC molecules where antigenic peptides are bound.
The longitudinal cleft in the top surface of an MHC molecule into which the antigenic peptide is bound. Sometimes called the peptide-binding groove
| Front | The longitudinal cleft in the top surface of an MHC molecule into which the antigenic peptide is bound. Sometimes called the peptide-binding groove |
|---|---|
| Back | peptide-binding cleft |
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