Purine nucleotide phosphorylase (PNP) deficiency is an enzyme defect causing intracellular accumulation of purine nucleosides toxic to developing T cells, resulting in severe combined immunodeficiency.
La deficiencia de purina nucleósido fosforilasa (PNP) es un defecto enzimático que causa una acumulación intracelular de nucleósidos de purina tóxicos para las células T en desarrollo, resultando en inmunodeficiencia combinada grave.
| Front | An enzyme defect that results in severe combined immunodeficiency. This deficiency causes an intracellular accumulation of purine nucleosides, which are toxic to developing T cells |
|---|---|
| Back | purine nucleotide phosphorylase PNP deficiency |
Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.
Next card: Autoinflammatory syndrome caused mutations protein interacts pyrin pyogenic
Previous card: Dna form retrovirus integrated host-cell genome remain transcriptionally
Up to card list: Janeway's Immunobiology 9th Edition Concept Flash Card