Chimeric antigen receptor (CAR) refers to engineered fusion proteins composed of extracellular antigen-specific receptors (e.g., single-chain antibody) and intracellular signaling domains that activate and co-stimulate, expressed in Treg cells for cancer immunotherapy.
Chimere antigen receptor (CAR) is een engineered fusie-eiwit dat bestaat uit extracellulaire antigen-specifieke receptoren (bv. single-chain antilichaam) en intracellulaire signaaldomeinen die stimuleren. Deze worden tot expressie gebracht in Treg-cellen voor gebruik in kankerimmunotherapie.
| Front | Engineered fusion proteins composed of extracellular antigen-specific receptors e.g. single-chain antibody and intracellular signaling domains that activate and co-stimulate, expressed in Tregcells for use in cancer immunotherapy |
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| Back | chimeric antigen receptor CAR |
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