Factor I deficiency is a genetically determined lack of the complement-regulatory protein factor I. This results in uncontrolled complement activation, so that complement proteins rapidly become depleted. Those with the deficiency suffer repeated bacterial infections, especially with ubiquitous pyogenic bacteria.
La deficiencia del factor I es una falta genética del factor regulador del complemento I. Esto resulta en una activación descontrolada del complemento, por lo que las proteínas del complemento se agotan rápidamente. Los que tienen la deficiencia sufren infecciones bacterianas repetidas, especialmente con bacterias piógenas ubicuas.
| Front | A genetically determined lack of the complement-regulatory protein factor I. This results in uncontrolled complement activation, so that complement proteins rapidly become depleted. Those with the deficiency suffer repeated bacterial infections, especially with ubiquitous pyogenic bacteria |
|---|---|
| Back | factor I deficiency |
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