AIRE encodes the autoimmune regulator protein, involved in expressing genes by thymic medullary epithelial cells to promote tolerance to self-antigens.
AIRE codifica la proteína reguladora autoinmune, involucrada en la expresión de genes por células epiteliales medulares tímicas para promover tolerancia a autoantígenos.
| Front | Gene encoding a protein autoimmune regulator that is involved in the expression of numerous genes by thymic medullary epithelial cells, enabling developing T cells to be exposed to self proteins characteristic of other tissues, thereby promoting tolerance to these proteins. Deficiency of this gene leads to an autoimmune disease, APECED |
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| Back | AIRE |
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