The affinity hypothesis proposes how the choice between negative and positive selection of T cells in the thymus is made, based on the strength of self-peptide:MHC binding by the T-cell receptor.
La hipótesis de afinidad propone cómo se toma la decisión entre selección negativa y positiva de células T en el timo, basándose en la fuerza de la unión entre el receptor de células T y el ligando de péptido propio:MHC.
Front | Hypothesis that proposes how the choice between negative selection and positive selection of T cells in the thymus is made, according to the strength of self-peptide:MHC binding by the T-cell receptor |
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Back | affinity hypothesis |
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