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Immune Response Mhc Molecules Archaic Term Genetic Polymorphisms

Immune response (Ir) genes, an archaic term, refer to non-MHC antigens causing strong T cell responses to allogeneic cells, now understood to be superantigens encoded by endogenous retroviruses.

An archaic term referring to non-MHC antigens responsible for unusually strong T cell responses to cells from different strains of mice, now known to be superantigens encoded by endogenous retroviruses

Front An archaic term for genetic polymorphisms controlling the intensity of the immune response to a particular antigen, now known to result from allelic differences in MHC molecules, especially MHC class II molecules, that influence binding of particular peptides
Back Ir immune response genes

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