IRAK4 deficiency is an immunodeficiency characterized by recurrent bacterial infections, caused by inactivating mutations in the IRAK4 gene that result in a block in TLR signaling.
La deficiencia de IRAK4 es una inmunodeficiencia caracterizada por infecciones bacterianas recurrentes, causada por mutaciones inactivadoras en el gen IRAK4 que resultan en un bloqueo en la señalización de TLR.
| Front | An immunodeficiency characterized by recurrent bacterial infections, caused by inactivating mutations in the, IRAK4, gene that result in a block in TLR signaling |
|---|---|
| Back | IRAK4 deficiency |
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