Chronic granulomatous disease (CGD) is an immunodeficiency in which multiple granulomas form as a result of defective elimination of bacteria by phagocytic cells. It is caused by defects in the NADPH oxidase system of enzymes that generate the superoxide radical involved in bacterial killing.
La enfermedad granulomatosa crónica (CGD) es una inmunodeficiencia en la que se forman múltiples granulomas como resultado de la eliminación defectuosa de bacterias por células fagocíticas. Es causada por defectos en el sistema de enzimas NADPH oxidasa que generan el radical superóxido involucrado en la eliminación de bacterias.
| Front | An immunodeficiency in which multiple granulomas form as a result of defective elimination of bacteria by phagocytic cells. It is caused by defects in the NADPH oxidase system of enzymes that generate the superoxide radical involved in bacterial killing |
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| Back | chronic granulomatous disease CGD |
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