Tacrolimus (FK506) is an immunosuppressant polypeptide drug that binds FKBPs and inactivates T cells by inhibiting calcineurin, thereby blocking activation of the NFAT transcription factor.
El tacrolimus (FK506) es un fármaco inmunosupresor polipeptídico que se une a FKBPs e inactiva células T inhibiendo la calcineurina, bloqueando así la activación del factor de transcripción NFAT.
| Front | An immunosuppressant polypeptide drug that binds FKBPs and inactivates T cells by inhibiting calcineurin, thus blocking activation of the transcription factor NFAT. Also called FK506 |
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| Back | tacrolimus |
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