Adenosine deaminase (ADA) deficiency is an inherited defect leading to the accumulation of toxic purine nucleosides and nucleotides in cells, resulting in the death of most developing lymphocytes within the thymus.
La deficiencia de adenosina deaminasa (ADA) es un defecto hereditario que causa la acumulación de nucleósidos y nucleótidos de purina tóxicos en las células, resultando en la muerte de la mayoría de los linfocitos en desarrollo en el timo.
| Front | An inherited defect which leads to the accumulation of toxic purine nucleosides and nucleotides in cells, resulting in the death of most developing lymphocytes within the thymus. It is a cause of severe combined immunodeficiency |
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| Back | adenosine deaminase ADA deficiency |
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