Griscelli syndrome is an inherited immunodeficiency affecting the pathway for lysosome secretion, caused by mutations in the GTPase Rab27a, affecting cellular vesicle movement.
El síndrome de Griscelli es una inmunodeficiencia heredada que afecta la vía de secreción de lisosomas, causada por mutaciones en la GTPasa Rab27a, afectando el movimiento de vesículas celulares.
| Front | An inherited immunodeficiency disease that affects the pathway for secretion of lysosomes. It is caused by mutations in a small GTPase Rab27a, which controls the movement of vesicles within cells |
|---|---|
| Back | Griscelli syndrome |
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