STING (stimulator of interferon genes) is a dimeric cytoplasmic protein complex anchored to the ER membrane that senses infection by activating TBK1, which then phosphorylates IRF3 to induce type I interferon genes.
A dimeric protein complex in the cytoplasm anchored to the ER membrane that functions in intracellular sensing for infection. It is activated by specific cyclic di-nucleotides to activate TBK1, which phosphorylates IRF3 to induce transcription of type I interferon genes
| Front | A dimeric protein complex in the cytoplasm anchored to the ER membrane that functions in intracellular sensing for infection. It is activated by specific cyclic di-nucleotides to activate TBK1, which phosphorylates IRF3 to induce transcription of type I interferon genes |
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| Back | STING stimulator of interferon genes |
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