Leukocyte adhesion deficiencies (LADs) are a class of immunodeficiency diseases in which the ability of leukocytes to enter sites infected by extracellular pathogens is affected, impairing elimination of infection. There are several different causes, including a deficiency of the common β chain of the leukocyte integrins.
Las deficiencias de adhesión de leucocitos (LADs) son una clase de enfermedades de inmunodeficiencia en las que la capacidad de los leucocitos para entrar en sitios infectados por patógenos extracelulares se ve afectada, lo que dificulta la eliminación de la infección. Hay varias causas diferentes, incluyendo una deficiencia de la cadena β común de las integrinas de leucocitos.
| Front | A class of immunodeficiency diseases in which the ability of leukocytes to enter sites infected by extracellular pathogens is affected, imparing elimination of infection. There are several different causes, including a deficiency of the common β chain of the leukocyte integrins |
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| Back | leukocyte adhesion deficiencies LADs |
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