S1PR1 is a G protein-coupled receptor expressed on circulating lymphocytes that binds the chemotactic phospholipid sphingosine 1-phosphate (S1P), controlling the egress of non-activated lymphocytes from secondary lymphoid tissues.
S1PR1 es un receptor acoplado a proteína G expresado en linfocitos circulantes que se une al fosfolípido quimiotáctico, la esfingosina 1-fosfato (S1P), controlando la salida de linfocitos no activados de los órganos linfoides secundarios.
Front | A G protein-coupled receptor expressed on circulating lymphocytes that binds the chemotactic phospholipid, sphingosine 1-phosphate, which forms a chemotactic gradient that promotes the egress of non-activated lymphocytes out of secondary lymphoid tissues into the efferent lymphatics and blood |
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Back | S1PR1 |
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