IFI16 (interferon-γ-inducible protein 16) is a member of the PYHIN subfamily of NLR (NOD-like receptor) proteins that contains an N-terminal HIN domain. It activates the STING pathway in response to double-stranded DNA.
IFI16 (proteína 16 inducida por IFN-γ) es un miembro de la subfamilia PYHIN de receptores tipo NOD (NLR) que contiene un dominio HIN N-terminal. Activa la vía STING en respuesta a ADN de doble cadena.
| Front | A member of the PYHIN subfamily of NLR NOD-like receptor family containing an N-terminal HIN domain. It activates the STING pathway in response to double-stranded DNA |
|---|---|
| Back | IFI16 IFN-γ-inducible protein 16 |
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