Question

A pathway for NFκB activation that is distinct from the one activated by antigen receptor stimulation. This pathway leads to activation of the NFκB-inducing kinase, NIK, which phosphorylates and activates IκB kinase α IKKα inducing cleavage of the NFκB precursor protein p100 to form the active p52 subunit

Accepted Answer

non-canonical NFκB pathway

Front	A pathway for NFκB activation that is distinct from the one activated by antigen receptor stimulation. This pathway leads to activation of the NFκB-inducing kinase, NIK, which phosphorylates and activates IκB kinase α IKKα inducing cleavage of the NFκB precursor protein p100 to form the active p52 subunit
Back	non-canonical NFκB pathway

Pathway Nfκb Activation Distinct Activated Antigen Receptor Stimulation