TNF-receptor associated periodic syndrome (TRAPS) is an autoinflammatory disease characterized by recurrent episodes of inflammation and fever due to mutations in the TNFR-I gene, which activates TNF-α production.
El síndrome periódico asociado a receptores de TNF (TRAPS) es una enfermedad autoinflamatoria caracterizada por episodios recurrentes de inflamación y fiebre debidos a mutaciones en el gen TNFR-I, que activa la producción de TNF-α.
| Front | An\xa0autoinflammatory disease characterized by recurrent, periodic episodes of inflammation and fever caused by mutations in gene that encodes TNF receptor I. The defective TNFR-I proteins fold abnormally and accumulate in cells in such a way that they spontaneously activate production of TNF-α |
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| Back | TNF-receptor associated periodic syndrome TRAPS |
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