STIM1 is a transmembrane protein that acts as a Ca2+ sensor in the endoplasmic reticulum; when Ca2+ is depleted from the ER, STIM1 activates and induces opening of plasma membrane CRAC channels.
STIM1 es una proteína transmembrana que actúa como sensor de Ca2+ en el RE; cuando el Ca2+ se agota en el RE, STIM1 se activa e induce la apertura de canales CRAC de la membrana plasmática.
| Front | A transmembrane protein that acts as a Ca, 2+, sensor in the endoplasmic reticulum. When Ca, 2+, is depleted from the endoplasmic reticulum, this protein is activated and induces opening of plasma membrane CRAC channels |
|---|---|
| Back | STIM1 |
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