B7 molecules (B7.1 and B7.2) are cell-surface proteins on specialized antigen-presenting cells such as dendritic cells, which are the major co-stimulatory molecules for T cells. These cell surface proteins are closely related members of the immunoglobulin superfamily and both bind to the CD28 and CTLA-4 proteins on T cells.
Las moléculas B7 (B7.1 y B7.2) son proteínas de la superficie celular en células presentadoras de antígenos especializadas como las células dendríticas, que son las principales moléculas coestimulatorias para las células T. Estas proteínas de la superficie celular son miembros estrechamente relacionados de la superfamilia de inmunoglobulinas y ambas se unen a las proteínas CD28 y CTLA-4 en las células T.
| Front | Cell-surface proteins on specialized antigen-presenting cells such as dendritic cells, which are the major co-stimulatory molecules for T cells. These cell surface proteins are closely related members of the immunoglobulin superfamily and both bind to the CD28 and CTLA-4 proteins on T cells |
|---|---|
| Back | B7 molecules, B7.1 and B7.2 |
Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.
Next card: Dendritic c-type lectin expressed selectively receptor surface human
Previous card: Diseases due unregulated inflammation absence infection variety including
Up to card list: Janeway's Immunobiology 9th Edition Concept Flash Card