PD-1 (Programmed death-1) is a receptor on T cells that, upon binding its ligands PD-L1 and PD-L2, inhibits antigen receptor signaling and is a target for cancer therapies aimed at stimulating T-cell responses to tumors.
PD-1 (muerte programada-1) es un receptor en células T que, al unirse a sus ligandos PD-L1 y PD-L2, inhibe la señalización del receptor de antígeno; es un objetivo de terapias contra el cáncer para estimular respuestas T contra tumores.
| Front | A receptor on T cells that when bound by its ligands, PD-L1 and PD-L2, inhibits signaling from the antigen receptor. This receptor contains an ITIM motif in its cytoplasmic tail. Target of cancer therapies aimed at stimulating T-cell responses to tumors |
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| Back | PD-1 Programmed death-1 |
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