FcγRIII are cell-surface receptors that bind the Fc portion of IgG molecules, distinguishing aggregated from free IgG. They are expressed on phagocytes, B lymphocytes, NK cells, and follicular dendritic cells, playing a key role in humoral immunity.
FcγRIII son receptores de superficie celular que se unen a la porción Fc de las moléculas IgG, distinguiendo IgG agregada de la libre. Se expresan en fagocitos, linfocitos B, células NK y células dendríticas foliculares, desempeñando un papel clave en la inmunidad humoral.
| Front | Cell-surface receptors that bind the Fc portion of IgG molecules. Most of these receptors bind only aggregated IgG, allowing them to discriminate bound antibody from free IgG. Expressed variously on phagocytes, B\xa0lymphocytes, NK cells, and follicular dendritic cells, these receptors have a key role in humoral immunity, linking antibody binding to effector cell\xa0functions |
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| Back | FcγRIII |
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