Hyperacute graft rejection is an immediate rejection reaction caused by preformed natural antibodies that react against antigens on the transplanted organ, triggering the blood-clotting cascade and leading to graft ischemia.
El rechazo hiperagudo del injerto es una reacción de rechazo inmediata causada por anticuerpos naturales preformados que reaccionan contra antígenos del órgano trasplantado, activando la cascada de coagulación y causando isquemia del injerto.
Front | Immediate rejection reaction caused by preformed natural antibodies that react against antigens on the transplanted organ. The antibodies bind to endothelium and trigger the blood-clotting cascade, leading to an engorged, ischemic graft and rapid death of the organ |
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Back | hyperacute graft rejection |
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