Radiation-sensitive SCID (RS-SCID) is severe combined immunodeficiency due to defects in DNA repair pathways, rendering cells unable to perform VDJ recombination and repair radiation-induced double-strand breaks.
El SCID sensible a la radiación (RS-SCID) es una inmunodeficiencia combinada grave debida a defectos en las vías de reparación del ADN, que impiden la recombinación VDJ y la reparación de roturas de doble cadena inducidas por radiación.
| Front | Severe combined immunodeficiency due to a defect in DNA repair pathways, which renders cells unable to perform VDJ recombination and unable to repair radiation-induced double-strand breaks |
|---|---|
| Back | radiation-sensitive SCID RS-SCID |
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