PKR is a serine/threonine kinase activated by IFN-α and IFN-β. It phosphorylates the eukaryotic protein synthesis initiation factor eIF-2, inhibiting translation and thus contributing to the inhibition of viral replication.
PKR es una serina/treonina quinasa activada por IFN-α e IFN-β. Fosforila el factor de iniciación de la síntesis de proteínas eucariota eIF-2, inhibiendo la traducción y contribuyendo así a la inhibición de la replicación viral.
| Front | Serine/threonine kinase activated by IFN-α and IFN-β. It phosphorylates the eukaryotic protein synthesis initiation factor eIF-2, inhibiting translation and thus contributing to the inhibition of viral replication |
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| Back | PKR |
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