Calcineurin is a cytosolic serine/threonine phosphatase crucial in T-cell receptor signaling; the immunosuppressive drugs cyclosporin A and tacrolimus inactivate it.
La calcineurina es una fosfatasa citosólica serina/treonina crucial en la señalización del receptor de células T; los fármacos inmunosupresores ciclosporina A y tacrolimus la inactivan.
| Front | A cytosolic serine/threonine phosphatase with a crucial role in signaling via the T-cell receptor. The immunosuppressive drugs cyclosporin A and tacrolimus inactivate this molecule, suppressing T-cell responses |
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| Back | calcineurin |
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