This flashcard defines clonal deletion as the process where immature lymphocytes that bind to self-antigens are eliminated, a key mechanism for developing self-tolerance in adaptive immunity.
A eliminação de linfócitos imaturos que se ligam a autoantigênios, o que produz tolerância ao próprio, conforme exigido pela teoria da seleção clonal da imunidade adaptativa. Este é o principal mecanismo da tolerância central e também pode ocorrer na tolerância periférica.
| Front | The elimination of immature lymphocytes when they bind to self antigens, which produces tolerance to self as required by the clonal selection theory of adaptive immunity. This is the main mechanism of central tolerance and can also occur in peripheral tolerance |
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| Back | clonal deletion |
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