Spt5 is a transcription elongation factor required for isotype switching in B cells, functioning with RNA polymerase to enable recruitment of AID to its targets in the genome.
Spt5 es un factor de elongación de la transcripción necesario para el cambio de isotipo en células B, que funciona con la ARN polimerasa para reclutar AID a sus objetivos genómicos.
| Front | A transcription elongation factor required for isotype switching in B cells that functions in associatioin with RNA polymerase to enable recruitment of AID to its targets in the genome |
|---|---|
| Back | Spt5 |
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