AP-1 is a heterodimeric transcription factor formed from Fos and Jun family members, activated by antigen receptor and TLR signaling, primarily activating cytokine and chemokine gene expression.
AP-1 es un factor de transcripción heterodimérico formado por miembros de las familias Fos y Jun, que se activa tras la señalización de receptores de antígenos y TLRs, principalmente activando la expresión de citoquinas y quimiocinas.
| Front | A heterodimeric transcription factor formed as one of the outcomes of intracellular signaling via the antigen receptors of lymphocytes and the TLRs of cells of innate immunity. Most often, contains one Fos-family member and one Jun-family member. This transcription factor mainly activates the expression of genes for cytokines and chemokines |
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| Back | AP-1 |
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