Bcr-Abl tyrosine kinase is a constitutively active tyrosine kinase fusion protein caused by a chromosomal translocation (the Philadelphia chromosome) between the Bcr and Abl tyrosine kinase genes, associated with chronic myeloid leukemia.
Bcr-Abl tyrosine kinase is een constitutief actief tyrosine kinase fusie-eiwit veroorzaakt door een chromosomale translocatie (het Philadelphia-chromosoom) tussen de Bcr- en Abl-tyrosine kinase genen, geassocieerd met chronische myeloïde leukemie.
Front | Constitutively active tyrosine kinase fusion protein caused by a chromosomal translocation—the Philadelphia chromosome—between, Bcr, with the, Abl, tyrosine kinase genes associated with chronic myeloid leukemia |
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Back | Bcr–Abl tyrosine kinase |
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