Complementarity-determining regions (CDRs) are hypervariable parts of immunoglobulin and T-cell receptor V domains that determine antigen specificity and contact the ligand.
Parts of the V domains of immunoglobulins and T-cell receptors that determine their antigen specificity and make contact with the specific ligand. These are the most variable part of antigen receptor, and contribute to the diversity of these proteins. There are three such regions CDR1, CDR2, and CDR3 in each V domain
| Front | Parts of the V domains of immunoglobulins and T-cell receptors that determine their antigen specificity and make contact with the specific ligand. These are the most variable part of antigen receptor, and contribute to the diversity of these proteins. There are three such regions CDR1, CDR2, and CDR3 in each V domain |
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| Back | complementarity-determining regions CDRs |
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