The leading strand is continuously synthesized in the direction of the replication fork, read 3' to 5' and synthesized 5' to 3'. The lagging strand is synthesized in the opposite direction, with DNA polymerase unable to read its 5' to 3' polarity directly.
The leading strand is continuously synthesized in the direction of the replication fork, read 3' to 5' and synthesized 5' to 3'. The lagging strand is synthesized in the opposite direction, with DNA polymerase unable to read its 5' to 3' polarity directly.
| Text | The leading strand in each replication fork is the strand that is copied in a continuous fashion, in the same direction as the advancing replication fork. This parental strand will be read 3' to 5' and its complement will be synthesized in a 5' to 3' manner. The lagging strand is the strand that is copied in a direction opposite the direction of the replication fork. This side has a 5' to 3' polarity, which the DNA polymerase cannot read |
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Tags: biochemistry_6
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