This flashcard describes the mechanism of ETEC's heat-labile toxin (LT), which activates adenylate cyclase, increasing cAMP and chloride/bicarbonate secretion in the small intestine, leading to watery diarrhea (FA mnemonic).
Cette flashcard décrit le mécanisme de la toxine thermolabile (LT) de l'ETEC, qui active l'adénylate cyclase, augmentant l'AMPc et la sécrétion de chlorure et de bicarbonate dans l'intestin grêle, entraînant une diarrhée lactée (FA mnemonic).
Front | Bugs with exotoxins: Bacteria that increase fluid secretion: Enterotoxigenic E Coli (ETEC) Toxin: Heat-labile toxin (LT) Mechanism: ____activates? (increase in?1) --> two secretory changes (and where?) Manifestation: 1 for labile (FA mnemonic) |
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